Novel Estimation of Left Ventricular Filling Pressure Using 3-D Speckle-Tracking Echocardiography: Assessment in a Decompensated Systolic Heart Failure Model

Abstract E/e′ allows for the non-invasive estimation of left ventricular (LV) filling pressure; however, Doppler malalignment can make unreliable, especially in dilated systolic failing hearts. The ratio peak early diastolic rate to global strain (FRe/SRe), which is a parameter derived from 3-D speckle-tracking echocardiography estimate pressure, may be better applied hearts because it obtained without method. We investigated whether FRe/SRe could provide pressure than E/e′ 23 dogs with decompensated heart failure induced by microembolization. had correlation coefficients LV end-diastolic (0.75–0.90) did (0.40). diagnostic accuracy distinguishing elevated was significantly higher that E/e′. This study indicates